Pneumatic dry granulation(7)
As mentioned above, RC is designed to improve the flow properties, increase the bulk density and ensure the uniformity of particulate formulations by preventing segregation. It offers advantages compared to wet granulation for processing physically or chemically moisture-sensitive materials because granulation liquid is not needed. Another advantage is that it does not require a drying stage and is, therefore, suitable for use with compounds that either have a low melting point or degrade rapidly on heating, thus, making it a cost-effective manufacturing option.

